| In mammals, it is known as a cellular communication pathway that is involved in such factors as multiplication, apoptosis,
and the determination of a cell's fate, the Notch pathway is essential. In order for the visual system to work properly, (RPE)
cells are essential. Notch signaling was studied in this study. In RPE cells, we observed a differential expression of
components that belong to the Notch signaling Indicators of progress. As a result of blocking the Notch Indicators of
progress, RPE cells were unable to migrate and reproduce and some Notch signaling target genes, including various types,
were reduced in expression levels. In RPE cells, Notch signaling appears to play a critical role, suggesting a novel
approach to treating ophthalmic diseases involving RPE cells might involve targeting Notch signaling.ddd |
