This original research article aims to comprehensively examine the prevalence and determinants of depressive symptoms
among individuals undergoing maintenance hemodialysis, providing insights into the multifaceted interactions between
chronic kidney disease and mental health. A cross-sectional clinical study was conducted, involving 75 adult patients
undergoing maintenance hemodialysis. Standardized assessments were employed to gauge depressive symptoms, while
demographic, clinical, and treatment-related data were systematically collected. Statistical analyses, including logistic
regression, were utilized to identify key factors contributing to depressive symptoms. The study uncovered a notable
prevalence of depressive symptoms among patients undergoing maintenance hemodialysis, with 57 patients experiencing
clinically significant levels. Significantly associated factors included the duration of hemodialysis, presence of comorbid
medical conditions, and socioeconomic status. The impact of depressive symptoms on treatment adherence and overall
quality of life was explored, revealing noteworthy implications.This clinical study offers crucial insights into the
prevalence and determinants of depressive symptoms in the maintenance hemodialysis patient population. The findings
underscore the imperative for routine screening and targeted interventions to address mental health challenges in this
vulnerable cohort. Integrating mental health support into the holistic care of individuals on maintenance hemodialysis may
enhance treatment adherence and overall well-being, thereby improving patient outcomes. Further longitudinal
investigations are warranted to elucidate the dynamic nature of depressive symptoms in this population and assess the
efficacy of tailored interventionsddd |