| C-reactive protein (CRP) is an acute phase protein synthesized in response to tissue damage or inflammation and reflects
total systemic burden of inflammation in individuals. Introduction Asthma is an inflammatory disorder of the airways that
involves several inflammatory cells and multiple mediators that result in characteristic pathophysiological changes. The
airway inflammation in asthma is persistent even though symptoms are episodic. The study was conducted on 100
consecutive patients diagnosed as having bronchial asthma and admitted in the Deccan College of Medical Sciences,
Hyderabad, and Sri Lakshmi Narayana Institute of Medical Sciences, Pondicherry. The study suggests that there exists a
certain degree of low-grade systemic inflammation in addition to the local bronchial inflammation in non-atopic
asthmatics. Hence, hs-CRP may be used as a surrogate marker for the airway inflammation in non-atopic asthma patients.
There is an association between airway inflammation in bronchial asthma and systemic inflammationddd |
