Hypoparathyroidism is one of the most common side effects of complete thyroid surgery, and it occurs when the parathyroid gland tissue is devascularized, directly injured, or removed unintentionally. Hypoparathyroidism is responsible for more than half of all hospital readmissions of patients that have had thyroid surgery. In 6% to 59 percent of cases, transient hypocalcemia lasts 6 months or less after surgery, whereas permanent hypoparathyroidism can last up to 5.5 percent of patients.Also in the presence of seasoned surgeons, unintentional parathyroidectomy happens in 1% to 31% of instances. The aim of this study was hypothesised that factors complicating dissection, such as inflammation and hypervascular states, would increase the rate of unintended parathyroidectomy.The involvement of hyperthyroidism (n 117, 46.8% 0.26), 0.72), or concomitant hyperparathyroidism (3, 1.2%, p= 0.25) had no effect on the incidence of accidental parathyroidectomy the central neck dissection has the greatest impact on parathyroid failure (odds ratio 4.72 (confidence interval 1.91–11.71], P 14 0.0008), according to multivariable analysis. Finally, performing a central neck dissection is the biggest risk factor for accidental parathyroidectomy. Unintentional parathyroidectomy does not seem to be more common in patients with lymphocytic thyroiditis, hyperthyroidism, or concomitant primary hyperparathyroidismddd |