The antibacterial activity of the ethanol, and aqueous extracts from the fruit of A. marmelos was studied using disc
diffusion method against five pathogenic bacterial strains, three Gram-positive bacteria (B. cereus, S. epidermidis, S.
aureus) and two Gram-negative bacteria (E. aerogens, K. pneumoniae). The maximum 14.3 mm zone of inhibition was
observed at the concentration of 40mg/ml for aqueous extract. This may be due to the presence of the compounds
Cuminaldehyde and Eugenol. In the case of ethanol, the maximum antibacterial activity was seen against E. aerogens
followed by S. epidermidis and K. pneumonia. At the highest concentration of 160 mg/ml, it showed 18.3mm zone of
inhibition. The antibiotic susceptibility showed that among all the bacterial strains S. aureus was found more susceptible to
ampicillin followed by K. pneumonia. Results suggest that the ethanolic extract has significant antibacterial activity against
tested bacteria. The present study justifies the claimed uses of A. marmelos in the traditional system of medicine to treat
various infectious diseases.ddd |