ABSTRACT
Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. A regular and widespread use of herbs throughout the world has increased serious concerns over their quality, safety and efficacy. Thus, a proper scientific evidence or assessment has become the criteria for acceptance of herbal health claims. Azadirachta indica L. (Meliaceae) widely distributed because of both religious and medicinal applications. We examined the effect of ethanol extract of roots of Azadirachta indica 25, 50, 100mg/kg doses orally in the isolated goat tracheal chain preparation, passive paw anaphylaxis in rat. The extract showed significant dose-dependent antiasthmatic activity in all these models.

Keywords: Antiasthmatic activity, Azadirachta indica , Meliaceae