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EVALUATION OF TRANSDERMAL FENTANYL PATCH FOR THE CONTROL OF POST OPERATIVE ANALGESIA

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ABSTRACT
Aim is to compare the quality and duration of post-operative analgesia 40 patients were randomly allocated into 2 group. Group F: Transdermal fentanyl patch releasing 25microgram/hr of fentanyl Group P: Placebo patch of same size. Patches were applied 4-6 hours before surgery. Heart Rate, Blood Pressure and Oxygen Saturation was recorded during surgery. At approximately 30 minutes before the end of the surgery, Inj Diclofenac 2mg/kg IV given to the patients. Rescue analgesic (Inj. Diclofenac 2mg/kg IV) was given to patients if they complain of pain or if VAS score greater than 4 postoperatively. Duration of analgesia was longest with group f (fentanyl) without any significant side effect. Conclusion is Low dose transdermal fentanyl patch releasing 25μg/hr fentanyl is safe and effective alternative for postoperative analgesia results in significant reduction in postoperative pain score and significantly decrease in requirement of supplementary analgesic postoperatively without any clinically evident respiratory depression. Stastical Analysis Used: Student T test.
Key words: Fentanyl Patch, Post-Operative Analgesia.

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