ABSTRACT
The purpose of this review is to provide an update on the current knowledge within this field of ocular drug delivery. Drug delivery to eye has always been a daunting task in the field of pharmaceutical research due to unique anatomy and physiology of the eye. Innovatory novel therapy for treatment of ocular diseases has emerged due to the recent advance in drug delivery approaches and material sciences. In the earlier periods, drug delivery to the eye has been limited to topical application, redistribution into the eye following systemic administration or directs intraocular/periocular injections. Conventional drug delivery systems: which include solutions, suspensions, gels, ointments and inserts, suffer with the problems such as poor drainage of instilled solutions, tear turn over, poor corneal permeability, nasolacrimal drainage, systemic absorption and blurred vision. Nano carrier based approaches seem to be most attracting and are extensively investigated presently.
Key words: Ocular drug delivery, Eye medications, Side effects.